Two Wrongs Make a Right: How Two Damaging Variants Can Restore Health 

In a groundbreaking study published in the Proceedings of the National Academy of Sciences, scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease. Instead, the team found that, in many cases, two harmful variants can actually restore normal protein function.