PNRI’s Science Matters Seminar – A Retrotransposon in Cancer: The Marker and The Mutator

Join Kathleen Burns, MD, PhD, Chair of Pathology at Dana-Farber Cancer Institute and Professor of Pathology at Harvard Medical School as she discusses the intriguing world of repetitive DNA sequences within the human genome, focusing on the utility of using the LINE-1 ORF1 protein as a cancer biomarker. She will also explore the mechanisms and implications of LINE-1 ORF2 mutagenesis in various malignancies.

PNRI’s Science Matters free, virtual seminars feature discussions with scientists around the globe about exciting research in genetics, genomics, and evolutionary biology with important societal impact.  Topics include research on the genetics of ethnically diverse populations, diseases afflicting vulnerable or underserved groups, and efforts to expand the diversity (broadly defined) of research subjects or the scientific workforce.