Seattle biotech startup Phase Genomics is receiving $1.5M from the Bill & Melinda Gates Foundation to fund research into two important areas: killing drug-resistant bacteria and battling methane-producing microorganisms that live in the guts of cows and other ruminants.
The new grant will support a year-long project to create an antimicrobial discovery platform to tackle these challenges. The focus is on Campylobacter infections, which are among the most common human infections and can cause severe diarrhea. Methane released in cow burps are the No. 1 source of greenhouse gases for the agricultural sector.
The startup’s work is centered on bacteriophages, or phages, which are viruses that infect bacteria and as well as other microorganisms known as archaea. The phages produce proteins called lysins that target specific bacteria.